N-[4-(3-pyridinyl)phenyl]-4-morpholinepentanamide

N-[4-(3-pyridinyl)phenyl]-4-morpholinepentanamide - Names and Identifiers

Name	N-[4-(3-pyridinyl)phenyl]-4-morpholinepentanamide
Synonyms	SEN 12333 N-[4-(3-pyridinyl)phenyl]-4-morpholinepentanamide
CAS	874450-44-9

N-[4-(3-pyridinyl)phenyl]-4-morpholinepentanamide - Physico-chemical Properties

Molecular Formula	C20H25N3O2
Molar Mass	339.43
Storage Condition	-20℃
Use	SEN-12333, also known as WAY-31753, is is a selective agonist of the alpha(7) nAChR (EC50 = 1.6 μM, Ki = 260 nM at rat α7 nAChRs). SEN-12333 displayed excellent in vitro and in vivo profiles, excellent brain penetration and oral bioavailability, and demonstrates in vivo efficacy in multiple behavioural cognition models.

N-[4-(3-pyridinyl)phenyl]-4-morpholinepentanamide - Reference

Reference

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